@article{oai:seirei-univ.repo.nii.ac.jp:00001959, author = {YASUDA, Tomohiro and FUKUMURA, Kazuya and SATO, Yoshiaki and NAKAJIMA, Toshiaki}, issue = {1}, journal = {International Journal of KAATSU Training Research, International Journal of KAATSU Training Research}, month = {Apr}, note = {[Objective] It is well known that KAATSU resistance training can produce muscle hypertrophy without deteriorating cardiovascular system in older adults. However, it is unclear whether KAATSU resistance training exceeding 12 weeks were a highly safe and effective training method for improvement of skeletal muscle mass in older adults. We examined effect of 24 weeks of KAATSU resistance training on femoral muscle size and its safety for older adult. [Methods] The subject was an 84-year-old woman (standing height 153 cm and body weight 46 kg). The KAATSU resistance training was provided for a total of 48 sessions over 24 weeks. Training intensity and volume were set at 20% or 30% of one-repetition maximum (1-RM) and 75 repetitions for knee extension and leg press exercises, respectively. Mid-thigh muscle cross-sectional area (CSA) was measured by MRI scan before, 12 weeks, and 24 weeks after the training. The maximal strength, chair-stand test, hemodynamic parameters, arterial stiffness, coagulation system and muscle damage were also measured. [Results] Quadriceps muscle CSA, 1-RM strength and chair-stand test increased throughout 24-week training period. On the other hand, there were no changes in body weight, hemodynamic parameters (except for systolic blood pressure), arterial compliance coagulation system and muscle damage throughout the training period. [Conclusion] The 24 weeks of KAATSU resistance training may be a highly safe and effective training method for improvement of skeletal muscle mass in older adults.}, pages = {1--4}, title = {Effect of 24 weeks of KAATSU resistance training on femoral muscle size and safety in a 84-year-old woman.}, volume = {15}, year = {2020} }